Looks safe, but is it?

You’re invited to this free program: Swimming & Your Genes, starring Dr. David DeMarini, genetic toxicologist with the EPA. As summer approaches, we’re going to be discussing David’s research into swimming pools and drinking water.

In preparation, David was kind enough to share a little bit about himself.

Where did you grow up? Peoria, Illinois (yes, I played in Peoria). My father, Santa, ran a bar (I grew up in a tavern), and he was a first-generation Italian immigrant with only an 8th grade education.  My mom was a nurse (Irish from Iowa); it was a fun mix of cultures–we ate spaghetti with potatoes.  There are 4 boys, and 3 of us went into the health sciences (2 Ph.D. geneticists and 1 M.D. pulmonologist).

What did you want to be when you were a kid? A performer–anything would have been fine–singer, dancer, actor, musician (I’ve co-founded 2 theater companies, acted in a bunch of plays, and play piano–second-rate pop/B-way, and jazz).  My science career ended up satisfying my urge/need to perform–with lots of world-wide invitations to speak and lecture–combining my love of science and my desire to entertain.

How did you get interested in science? I always was curious about how the world worked, and science seemed to provide the most satisfying explanations to me; and I was pretty good at science in school. However, the “magic moment” came during my last semester of my senior year of college when I took genetics (from the finest teacher of my life), and I was hooked–I found my muse and my bliss–environmental mutagenesis, which has become a nearly 40-year love affair.  (I ended up doing my M.S. and Ph.D. under that remarkable genetics teacher–Herman Brockman at Illinois State University.)

In one sentence, describe your job: I examine the air, water, soil, food, urine from people, etc. for mutagenic activity and try to determine the types of mutations such substances induce and how those mutations might cause human disease such as cancer.

What’s a special talent/trick/skill/hobby you have that your colleagues don’t know about? I learned to make “cappelletti in brodo” as a kid from my Italian grandmother (la mia nona).  It is a pasta stuffed with chicken, beef, cheese, and lemon zest that is cooked in a beef/chicken broth–peculiar to the region east of Firenze (Florence) where my family is from.  I make a huge batch every winter that lasts for 6 months (thank heavens for freezers), but I have never shared this delicacy with either friends or colleagues–it’s only for “la famiglia.”

If someone wrote you a blank check to explore any aspect of your field’s research, what would you want to do and why? I would incorporate mutagenesis testing of the air and water in this country to go along with the chemical monitoring of air and water that currently occurs in order for us to know how mutagenic and thus, potentially carcinogenic, our air and water really are–based on actual toxicology measurements.

Great answers, David. We’ll see you on Thursday. Please bring some “cappelletti in brodo.”

We hope to see all of you at the Back Bar in downtown Chapel Hill by 7pm. Remember to get there early for some delicious appetizers sponsored by Sigma Xi.

Thanks, Jonathan

Jonathan Frederick is director of the North Carolina Science Festival. He's ready for someone to invent teleportation.

Dr. David DeMarini, one of our cafe regulars (and fantastic question-asker of other scientists), is a genetic toxicologist with the EPA. On Thursday, June 2, he will be our featured presenter. Please join us for:

June's Carolina Science Cafe presenter

Chlorinated Chromosomes:  Swimming and Your Genes

You know your hair or skin can be affected by a dip in the pool–and you usually smell like chlorine after that refreshing swim.  But have you ever wondered what happens to your genes while you’re paddling around in the swimming pool?  Want to know what’s really in that water, and what chlorine may be doing to your chromosomes?  Maybe not, but if you’d like to find out, check out the Science Cafe at the the Back Bar at Top the Hill in downtown Chapel Hill at 7:00 p.m. on Thursday, June 2, 2011.

Dr. David DeMarini, a genetic toxicologist at the U.S. Environmental Protection Agency in RTP, and an AdjunctProfessor in the Dept. of Environmental Science & Engineering at UNC, will discuss the latest studies he and his colleagues have done on the mutagenicity and carcinogenicity of swimming pool water and drinking water.  Dr. DeMarini has been studying the ability of chlorinated water to induce mutations for 30 years, and he will share this pool of knowledge with you while you drink something other than chlorinated water.  Take the plunge, and join us at the next Science Cafe in Chapel Hill!

Thanks, David, for the puns. Stay tuned for more info about David in our next blog.

Jonathan

Jonathan Frederick is Morehead's science program manager. He has recently pledged to run at least 15 miles per week and his muscles hurt thinking about it.

to attend this month’s Carolina Science Cafe. But you can chat with one!

The Star of May's Carolina Science Cafe

On Thursday, May 12, at 7 p.m., Dr. Matt Ewend, head of neurosurgery at UNC, will be at the Back Bar in Downtown Chapel Hill, talking about his world. A world that includes awake surgeries, removing tumors, using the CyberKnife, and more. We’re really looking forward to this one!

As usual, our friends at Sigma Xi will be sponsoring some appetizers and special thanks to Dr. Charles Weiss for making this event possible.

To get to know Matt a little more, check out his answers to our questions:

Where did you grow up? Saginaw Michigan, son of an insurance agent and an advertising person.  No medical folks in the family

What did you want to be when you were a kid? My grandfather was a lawyer, and that’s what I wanted to do.  I thought I could be a trial attorney.   I also thought I would like to be a sports announcer.

How did you get interested in science? I got interested in science and medicine during high school, but no real epiphany moment. I was a math major in college and came at science through the math physics pathway.    I like the clean answers that math and physics often provided better than the fuzzy answers of some other sciences.

In one sentence, describe your job: Everyday I meet people facing difficult illnesses involving the brain; my job is to help them through these times compassionately.

What’s a special talent/trick/skill/hobby that you have that your colleagues don’t know about? I got my privates pilot’s license a year ago and I am working on my instrument rating.  As a kid, I was almost as fast as Holden Thorp with Rubik’s cube.

If someone wrote you a blank check to explore any aspect of your field’s research, what would you want to do and why? I started out in medicine with an interest in cancer and this has never changed.  Given our mythical blank check, I would build a team to look at brain tumors on an individual level (think personalized medicine) to find newer targeted treatments.

Thanks, Matt, for taking the time to answer our questions.

We hope to see everyone on Thursday, 5/12, 7 p.m. at the Back Bar!

Cheers,

Jonathan


Jonathan Frederick is the director of the North Carolina Science Festival. He is currently reading East of Eden.